Movies from these publications Egeblad, M., A. J. Ewald, H. A. Askautrud, B. E. Welm, M. Truitt, E. Bainbridge, G. Peeters, M. Krummell & Z. Werb (2008). Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Disease Models Mech. 1:155-167. Ewald, A.J., A. Brenot, M. Duong, B.S. Chan & Z. Werb (2008). Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev. Cell. 14:570-581. Welm, B.E., G.J.P. Dijkgraaf, A.S. Bledau, A.L. Welm & Z. Werb (2008). Lentiviral Transduction of Mammary Stem Cells for Analysis of Gene Function during Development and Cancer. Cell Stem Cell 2008 2: 90-102.
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CD11c+ dendritic-like cells migrate at the tumor-stroma border, but not deeper within the tumor mass
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Infiltration and migration of c-fms+ myeloid cells vary with the tumor microenvironment
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Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia
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Carcinoma-associated fibroblasts in different tumor microenvironments
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Movie 1. Branching Organoid
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Movie 2. Lumen Clearing
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Movie 4. Ductal Initiation
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Movie 6. Transition from Multilayered to Single-Layered Epithelium in the Elongating Tips
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Movie 7. Cells Dynamically Rearranging within an Elongating Duct
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Movie 8. Cells Rearranging within an Elongating Duct as It Transitions from a Multilayer to a Single Layer
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Movie 10. MLCK Inhibitor Treated Organoid
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Movie 11. Control Organoid
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Movie 12. ROCK Inhibitor Treated Organoid
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Movie 15. ROCK Inhibitor Treated Organoid (3D Reconstruction)
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Movie 17. Addition (22 Hr) and Washout (69 Hr of Culture; 45 Hr into the Movie) of ROCK Inhibitor
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Alternating Red and Green Fluorescent Channels of Figure 3A of an Outgrowth from Mixed Red and Green Fluorescent MECs Transplanted at Nonlimiting Dilution that Contains Ducts with an Amalgamation of Fluorescent Patterns
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Alternating Red and Green Fluorescent Channels of Figure 3C of an Outgrowth from Mixed Red and Green Fluorescent MECs Transplanted at Nonlimiting Dilution that Contains Ducts with an Amalgamation of Fluorescent Patterns
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Alternating Red and Green Fluorescent Channels of Figure 3D of an Outgrowth from Mixed Red and Green Fluorescent MECs Transplanted at Nonlimiting Dilution that Contains Ducts with an Amalgamation of Fluorescent Patterns